Careers

Working at CDR-Life

CDR-Life is developing tumor-targeted immunotherapies to address unsolved problems in oncology by applying our LocATE antibody technology. To achieve our ambitious goals, we have created a dynamic working environment where we value curiosity, innovative thinking, committed teamwork, and the motivation to make an impact. We believe in trust and openness when doing our jobs, which may at times, take us beyond our comfort zones.

CDR-Life is a young biotech company giving our employees the opportunity to grow in their roles and have a direct impact on the development of novel therapies for people in urgent need. We are building a highly diverse team that collaborates across functions with a strong project focus and a flat hierarchy.

Open Positions

Technical Scientist Upstream Processing

Supporting the development of cell culture processes ready for transfer to clinical manufacturing

In this role, you will play an important part in the development of mammalian upstream processes ready for transfer to a manufacturing site. Moreover, you will help drive the establishment of a data-driven process development approach. We are looking for a highly motivated and collaborative individual with a passion for data-driven lab work, who enjoys working in a fast-paced and highly dynamic working environment.

Key Responsibilities

  • Planning, conducting, evaluating, and documenting experiments for the development of scalable and robust upstream processes for our antibody formats.
  • Production of drug candidates for internal developability programs as well as for in vivo studies.
  • Analysis of in-process cell culture samples to guide process development, e.g., Cedex Bio Analyzer, HPLC (application of established methods by the Analytics team).
  • Support the team in increasing cell cultivation capacities for efficient, fast-paced, and fully data-driven upstream development.
  • Responsible system owner for assigned equipment.

Your Profile

  • Apprenticeship with min. 3 years of working experience or BSc preferably in biochemistry, biotechnology or a related discipline.
  • Experience in mammalian cell cultivation and upstream process development for drug substance manufacturing in the pharmaceutical / biotech industry is essential.
  • Experience in key analytical methods for upstream process development, e.g., HPLC based titer methods and metabolite analytics etc.
  • Experience with non-standard antibody formats, as well as in mammalian cell line development is considered as a plus.
  • English (written and spoken) skills suitable for day-to-day interaction, documentation, and presentation of lab work.
  • Proven ability to work independently, as well as across teams’ boundaries.

Are you interested? For any further questions or your application please contact: daniel.kuhn@cdr-life.com. We are looking forward to hearing from you.

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Lab Support (80-100%)

Supporting daily lab activities crucial for our success

In this role, you will perform a variety of technical and administrative tasks to support Research and Development activities at CDR-Life. You will provide key services to enable efficient operations and ensure laboratory work continuity. The role requires a service- and solution-oriented mindset and a wish to conduct routine work in a reliable manner.

Key Responsibilities

  • Support routine laboratory maintenance such as glassware cleaning and autoclaving
  • Maintain inventories and prepare standard solutions (e.g., buffers, media, etc.) according to established methods and SOPs
  • Organize shipments of materials and samples
  • Receive parcels and deliveries
  • Help to maintain facility installations and keep track of key chemicals and consumables
  • Keep equipment in a clean and serviceable condition and ensure safe removal of waste
  • Support basic laboratory work

Your Profile

  • Experienced in a lab environment.
  • Proven ability to work independently, as well as across functions.
  • Hands-on mentality, conscientious, efficient, flexible and pro-active attitude
  • General understanding of the principles of biotechnological research and development is a plus.

Are you interested? For any further questions or your application please contact: wolfgang.kress@cdr-life.com

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Technical Scientist Small Scale Production (100%)

Production of antibody fragments to discover new first-in-class immuno-oncology drugs

You will play an important role in the production of antibodies and antibody-derived molecules in mammalian cell lines and collaborate with colleagues to deliver first-in-class biologics. In addition, you will help to drive innovative approaches for drug discovery using novel antibody and protein engineering technologies. We are looking for a highly motivated and collaborative individual with a passion for drug discovery research, who enjoys working in a fast-paced and highly dynamic working environment.

Responsibilities:

  • Perform transient transfection in mammalian cell cultures.
  • Execute various purification methods using state of the art Aekta systems.
  • Perform basic analytical methods such as SDS PAGE and SE-HPLC.
  • Support/perform production of animal trial material with low endotoxin levels.
  • Plan and execute plasmid cloning and DNA purification activities.
  • Ensure best practices of research, data management, and archiving.
  • Proactively prepare and/or organize required equipment, consumables, and reagents.

Your Profile:

  • Apprenticeship, BS, MSc. or equivalent in biology, biochemistry or a related discipline.
  • Demonstrated expertise in protein purification is essential.
  • Experience in mammalian cell culture techniques is essential.
  • Experience in basic analytical methods such as SE-HPLC and SDS PAGE.
  • Experience in basic molecular biology techniques.
  • Experience in endotoxin free protein production would be a plus.
  • Ability to work independently in a team environment.
  • Positive and proactive attitude.

Interested? Please send your documents to thomas.schleier@cdr-life.com. We look forward to receiving your application.

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