Careers

Working with us

CDR-Life is a young, dynamic biotech company that fosters growth and impact for its employees. We are building a highly diverse team that collaborates across functions and cultures. We foster a culture with a flat hierarchy and believe that we can only achieve success by working together collectively. If you are highly collaborative, goal oriented and mission driven, join our accomplished team us as we champion our M-gager® platform technology for the development of new, highly cancer-specific immunotherapies.

Open Positions

Technical Scientist/Research Associate Upstream Processing

Supporting the development of cell culture processes for clinical manufacturing

In this role, you will play an important part in the development and scale-up of mammalian upstream processes for CDR-Life’s M-gager® antibody formats ready for process transfer to a clinical manufacturing site. Moreover, you will help to drive the establishment of a data-driven process development approach. We are looking for a highly motivated and collaborative individual with a passion for data-driven lab work, who enjoys working in a fast-paced and highly dynamic working environment.

Key Responsibilities

  • Planning, conducting, evaluating, and documenting experiments for the development of scalable and robust upstream processes.
  • Optimization of mammalian cell cultivation in shake flasks and stirred-tank bioreactors for efficient production of our antibody formats.
  • Production of drug candidates for internal developability activities as well as for in vivo studies.
  • Analysis and interpretation of in-process cell culture samples to guide process development, e.g., Cedex Bio Analyzer, and HPLC.
  • Responsible system owner for assigned equipment.

Your Profile

  • Apprenticeship with min. 3 years of working experience, BSc or MSc preferably in biochemistry, biotechnology or a related discipline.
  • Experience in mammalian cell cultivation and upstream process development in the pharmaceutical / biotech industry.
  • Hands-on experience with stirred-tank bioreactors on lab- to pilot-scale.
  • Experience in key analytical methods for upstream process development, e.g., HPLC based titer methods and metabolite analytics etc. 
  • English (written and spoken) skills suitable for day-to-day interaction, documentation, and presentation of lab work.
  • Proven ability to work independently, as well as across teams’ boundaries.

Are you interested? For any further questions or your application please contact: rouven.bingel-erlenmeyer@cdr-life.com. We are looking forward to hearing from you. 

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Lab Technician Protein Purification (100%)

Produce proteins to support the research unit in generating first-in-class immune-oncology drugs

You will play an important role in the small scale production of antibodies and antibody derived molecules in mammalian cell cultures and collaborate with colleagues to deliver first-in-class biologics. In addition, you will help to drive innovative approaches for drug discovery using novel antibody and protein engineering technologies. We are looking for a highly motivated and collaborative individual with a passion for drug discovery research, who enjoys working in a fast-paced and highly dynamic working environment.

Responsibilities:

  • Perform transient transfection in mammalian cell cultures.
  • Perform various purification methods using state of the art Aekta systems.
  • Perform basic analytical methods such as SDS PAGE, IEX and SE-HPLC.
  • Support/perform production of endotoxin low proteins.
  • Support cloning activities.
  • Ensure best practices of research, data management and archiving.
  • Proactively prepare and/or organize required equipment, consumables and reagents.

Your Profile:

  • Technician with an apprenticeship or equivalent in Biology, Biochemistry or a related discipline.
  • Experience in mammalian cell culture techniques and small scale expression.
  • Demonstrated expertise in protein purification is essential.
  • Experience in basic analytical methods such as SE-HPLC and SDS PAGE.
  • Experience in basic molecular biology techniques would be a plus.
  • Experience in endotoxin free protein production would be a plus.
  • Ability to work independently in a team environment.
  • Positive and proactive attitude. 

Are you interested? For any further questions or your application please contact: thomas.schleier@cdr-life.com. We are looking forward to hearing from you. 

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Technical Scientist/Research Associate Downstream Processing

Supporting the development of scalable and robust processes, ready for tech transfer

In this role, you will play an important part in the development and scale-up of downstream processes for CDR-Life’s M-gager® antibody formats ready for process transfer to a clinical manufacturing site. Moreover, you will help drive the establishment of a data-driven process development approach. We are looking for a highly motivated and collaborative individual with a passion for data-driven lab work, who enjoys working in a fast-paced and highly dynamic working environment.

Key Responsibilities

  • Independent planning, execution, and evaluation of experiments for the development of scalable and robust downstream processes of our antibody formats.
  • Production of drug candidates for the developability programs as well as for in vivo studies.
  • Analysis of in-process samples to gather information on process development (mostly HPLC – applying methods established by the Analytics team).
  • Support the team in establishing high-throughput development systems and building up a fully data-driven process development platform.
  • Support of technology transfers to the clinical manufacturing site.
  • Responsible system owner for assigned equipment

Your Profile

  •  Apprenticeship with min. 3 years of working experience or BS, MSc. preferably in biochemistry, biotechnology or a related discipline.
  • Demonstrated experience in the development of state-of-the-art downstream processes for drug substance manufacturing in the pharmaceutical / biotech industry.
  • English (written and spoken) skills suitable for day-to-day interaction, documentation and presentation of lab work.
  • Proven ability to work independently, as well as across teams’ boundaries.
  • Positive and proactive attitude

Are you interested? For any further questions or your application please contact: daniel.kuhn@cdr-life.com. We are looking forward to hearing from you. 

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