You will be an integral part of the team by organizing and coordinating office administration to ensure smooth and effective day-to-day operations. This includes streamlining administrative procedures and carrying out office staff services in this growing start-up.  

We are looking for a positive and dynamic person who likes handling a wide range of general, administrative and support tasks. Able to work independently, you should be very well-organized, flexible, and enjoy supporting diverse and passionate people in different company areas.  

Responsibilities

Main

• Organizes offices, meeting rooms, and cafeteria including furniture and supplies  
• Organizes lunch deliveries and catering orders 
• Generates purchase orders and receives office deliveries  
• Provides supplier invoices to accounting 
• Administrates employee keys 
• Books dinner, hotel, and transfers for visitors 
• Receives guests 

Support

• Organization of larger internal or external meetings 
• Events organization  
• Onboarding of new hires 
• Travel bookings 

Your Profile

• Good communication skills 
• Proficient in MS Office and ideally MS SharePoint 
• Positive and proactive attitude 
• Well-organized and service-oriented 
• Likes to work independently 
• Fluent in English  
• A good command of German is a plus 
• Familiarity with pharma/biotech is a plus 

From May 2023, CDR-Life will be located at Tödistrasse 48, Horgen.

Are you interested? For any further questions or your application please contact: simona.cesari@cdr-life.com. We are looking forward to hearing from you.

You will play an important role in the screening and hit identification of antibodies and antibody-derived molecules while collaborating with colleagues to deliver first-in-class biologics. In addition, you will help to drive innovative approaches for drug discovery using novel antibody and protein engineering technologies. We are looking for a highly motivated and collaborative team member with a passion for drug discovery research, who enjoys working in a fast-paced and highly dynamic working environment.

Responsibilities:

• Execute and support antibody screening campaigns
• Perform phage display antibody library generation and selection
• Plan and execute molecular cloning activities
• Oversee ELISA-based binding characterization assays
• Perform FACS-based B-cell sorting and contribute to the development of the screening platform
• Cultivation and characterization of isolated B-cells
• Support activities for the design and optimization of antibody candidates
• Ensure best practices of research, data management and archiving
• Proactively prepare and/or organize required equipment, consumables and reagents

Your Profile:

• Apprenticeship, B.Sc. or MSc. in biology, biochemistry, immunology, or a related discipline
• Demonstrated expertise in antibody display techniques (e.g. phage, yeast or mammalian)
• Expertise in molecular biology and cell culture techniques
• Experience with ELISA assays for antibody characterization
• Laboratory experience in flow cytometry or FACS-based cell sorting is a plus
• Experience with antibody affinity maturation and antibody humanization would be a plus
• Experience in recombinant protein production using mammalian cells would be a plus
• Ability to work independently and well-organized in a team environment
• Positive and proactive mindset

Interested? Please send your documents to nagjie.alijaj@cdr-life.com. We look forward to receiving your application.

The successful candidate will develop and conduct state-of-the-art SPR-assays to guide the drug candidate selection of multi-specific antibodies from the initial high-throughput hit screening campaigns to in-depth characterization of selected clinical candidates. This includes kinetic parameter determinations, specificity characterizations, concentration measurements, batch release assays and the target preparation and evaluation. Your results will have an immediate impact on the work of cross-functional teams.  

We offer to work in a dynamic environment in a fast-growing biotech company with insight and contribution to the full preclinical pharmaceutical drug development process. By developing numerous different SPR-assays, you will gain profound knowledge in the field.

Key Responsibilities

• Independently develop, plan, and accurately execute SPR-assays on state-of-the-art devices
• Accurately and concisely document and present results and ensure data management
• Organize and maintain required equipment, consumables, and reagents
• Acquire information about new developments and technologies in the field
• Work collaboratively and flexibly to achieve project goals together as a team
• Support other biophysical characterization activities in the group (HPLC-assays, DSC etc.)

Your Profile

• Experienced BSc., or MSc. and equivalent in biology, chemistry, or a related discipline
• Solid protein biochemistry, protein handling and buffer knowledge is a must
• Accurate pipetting skills including the use of multichannel pipets and deep-well microplates
• Experience in analytical protein interaction measurements like ELISA or SPR-assays is a plus
• Well-organized, self-motivated, and able to work both independently and collaboratively in a dynamic team environment
• Active data-driven problem solver with the ability to question and optimize existing processes
• Fluency in written and spoken English

To apply or for any further questions please contact: hannes.merten@cdr-life.com. We are looking forward to hearing from you.

A central part of this role is the development, execution, and data analysis of in vitro potency and safety assays (e.g. cell killing, cytokine release) to support the selection and characterization of clinical candidates, with a particular focus on primary cells testing. The successful applicant will work in a matrix environment to drive scientific innovation collaboratively with other members of the Pharmacology & Discovery group, as well as with other functions including the Developability profiling group, CMC unit and external collaborators.

Responsibilities include, but are not limited to:

• Develop, optimize and conduct cell-based assays focused on characterization of T cell engagers
  • Co-culture assays with primary cells/cancer cell lines
  • T-cell proliferation/activation
  • Cytotoxicity and cytokine induction (LDH, CTG, Incucyte)
• Execute routine immunological, molecular, and cellular assays
• Perform ELISAs, cell-based assays, isolation of nucleic acids, and qPCR
• Analyze experiments using multicolor flow cytometry
• Independently analyze and present results to a diverse scientific audience
• Maintain and optimize mammalian cell culture processes

Qualifications:

• Laboratory Technician/B.Sc./M.Sc. with research experience in the fields of immunology and/or cancer immunotherapy, 2+ years industry experience
• Required previous experience in conducting cell-based assays and analysis of multiple immune endpoints (cytotoxicity, proliferation, cytokine levels)
• Experience with primary cells culture preferred
• Experience with 384 wells co-culture assay setups preferred 
• Experience with flow cytometry
• Use of analysis software GraphPad Prism
• Well-organized with an independent and accurate working style, ability to handle multiple tasks in parallel
• Positive, reliable, open-minded, and flexible team player with excellent communication skills
• Fluency in English

We are looking forward to receiving your application under stephanie.jungmichel@cdr-life.com